Severe allergic reaction after sipping energy drink traced to unexpected source
A 15-year-old boy was hospitalized after developing a severe allergic reaction, including widespread hives and difficulty breathing, after sipping a new energy drink.
A 15-year-old boy was hospitalized after developing a severe allergic reaction, including widespread hives and difficulty breathing, after sipping a new energy drink.
The case was presented at the American College of Allergy, Asthma and Immunology’s 2026 Annual Scientific Meeting in Phoenix, Arizona, on November 12–16.
The teen reported mild throat itching and lip swelling when eating canned tuna, but had eaten salmon without an issue. He also has eczema, asthma, and allergic rhinitis.
Unexpected source of reaction
A review of the drink’s label revealed it contained 5 grams of collagen derived from cod, a fish protein that can trigger allergic reactions in sensitive individuals.
This case shows how tricky fish allergy can be.
Standard fish allergy tests mostly look for a different fish protein and contain very little collagen, so a person can test negative and still react.
The teen was taken to the hospital, where he received two doses of epinephrine, albuterol, an antihistamine, and IV fluids before his symptoms resolved.
Growing use of fish collagen
Collagen from fish is showing up in a growing number of products, from drinks to supplements, according to the American College of Allergy, Asthma and Immunology.
Collagen from fish is showing up in a growing number of products, from drinks to supplements.
A spokesperson for the Council for Responsible Nutrition noted that collagen ingredients can come from several animal sources, like fish, cattle, and pigs.
While collagen has been studied for potential benefits related to skin and joint health, consumers should consider their individual health needs and sensitivities when choosing products.
Fish-derived collagen can pose an allergy risk for people sensitive to fish, and processing or hydrolysis does not necessarily eliminate that risk.
Label reading and consultation
Experts recommend that consumers with fish allergies carefully review product labels, which are required to identify major food allergens, such as fish.
Labels must identify the species of fish, and crustacean shellfish, such as shrimp, crab, and lobster, must also be specifically identified, according to the FDA.
For someone managing fish or shellfish allergy, 'marine collagen' on a label calls for a closer look at the ingredient list and 'contains' statement.
If the source still isn’t clear, FARE encourages people to call the manufacturer before using the product.
Consumers are encouraged to ask the manufacturer what the collagen is made from, and how the product is sourced, packaged, and tested for allergens.
This case offers a timely reminder to read every label, including on drinks and supplements, and talk with an allergist about any reaction, even if a test came back negative.
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